Treatment‐Related Mortality With Everolimus in Cancer Patients
نویسندگان
چکیده
منابع مشابه
Treatment-related mortality with everolimus in cancer patients.
INTRODUCTION The overall incidence and odds of fatal adverse events (FAEs) after exposure to everolimus are not well defined. We performed a comprehensive meta-analysis of published randomized controlled trials (RCTs) to determine the role of everolimus in treatment-related mortality in patients with cancer. METHODS PubMed databases and abstracts from the proceedings of the American Society o...
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BACKGROUND Two novel mammalian targets of rapamycin (mTOR) inhibitors everolimus and temsirolimus are now approved by regulatory agencies and have been widely investigated among various types of solid tumors, but the risk of fatal adverse events (FAEs) with these drugs is not well defined. METHODS We searched PubMed, EMBASE, and Cochrane library databases for relevant trials. Eligible studies...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2014
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2013-0355